More than 70 million couples suffer from infertility worldwide. One of the major causes of the decline in semen quality appears to be the elevated level of oxidative stress. Asthenozoospermia causes infertility because when sperm do not have progressive motility, they are unable to reach the egg and fertilize it. In recent years, the use of antioxidants in treatment of infertile men has been suggested, although there is limited evidence about the influence of nutrition on quality of semen. In this cohort study we aimed to evaluate the effect of vitamin C, vitamin E, zinc, selenium, L-Arginine, L-Carnitine, LMethionine and L-Phenylalanine on a male previously diagnosed with asthenozoospermia.
The man at age of 30, from Skopje, was supplemented twice daily with a tablet consisted of: Vitamin C (100 mg), Vitamin E (67 mg), Zinc (15 mg), Selenium (200 ug), L-Arginine (250 mg), L-Carnitine (50 mg), L-Methionine (50 mg) and LPhenylalanine (50 mg). Supplementation was done in a period of twelve weeks, from April to July 2017. Semen analysis with microscope phase-contrast was done in andrology laboratory in the policlinic “Bukutest”, with 3 days of abstinence, before and after treatment.
Before starting with the therapy, motility of spermatozoa was 35%, and according to referent values of this laboratory which uses WHO criteria of year 1999, classifies this man as asthenozoospermic. Second semen analysis was done twelve weeks after, and showed significant improvement of motility to 50% which meets the criteria of the WHO and considers the man as normozoospermic.
We assume that vitamin C, vitamin E, zinc, selenium, L-Arginine, L-Carnitine, L-Methionine and L-Phenylalanine intake could improve the motility of spermatozoa in men with asthenzoospermia and increases chances for fertilizing the egg.
Key words: Male infertility, Antioxidants, Semen quality, Asthenozoospermia.
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